Glaucoma is a heterogeneous group of disorders that progressively lead to blindness due to loss of retinal ganglion cells and damage\r\nto the optic nerve. It is a leading cause of blindness and visual impairment worldwide. Although research in the field of glaucoma is\r\nsubstantial, the pathophysiologic mechanisms causing the disease are not completely understood. A wide variety of animal models\r\nhave been used to study glaucoma. These include monkeys, dogs, cats, rodents, and several other species. Although these models\r\nhave provided valuable information about the disease, there is still no ideal model for studying glaucoma due to its complexity. In\r\nthis paper we present a summary of most of the animal models that have been developed and used for the study of the different\r\ntypes of glaucoma, the strengths and limitations associated with each species use, and some potential criteria to develop a suitable\r\nmodel.
Loading....